Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 11/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 11/20 | 0.47 |
| ▸ | FGFR3 | P22607 | 10/20 | 0.47 |
| ▸ | FGFR4 | P22455 | 6/20 | 0.47 |
| ▸ | ABL1 | P00519 | 4/20 | 0.46 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 6/20 | 0.44 |
| ▸ | FYN | P06241 | 4/20 | 0.44 |
| ▸ | LCK | P06239 | 2/20 | 0.44 |
| ▸ | RET | P07949 | 2/20 | 0.44 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | PLK4 | O00444 | 1/20 | 0.44 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | INSR | P06213 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | ROS1 | P08922 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18258364 | 0.93 | ABL1 (0.51) | FGFR2FGFR1FGFR3FGFR4ABL1 | |
| SCHEMBL4825100 | 0.84 | SRC (0.56) | FGFR2FGFR1FGFR3FGFR4SRC | |
| SCHEMBL4823820 | 0.81 | SRC (0.44) | FGFR2FGFR1FGFR3FGFR4ABL1 | |
| SCHEMBL18250080 | 0.78 | SRC (0.68) | ABL1PTK6SRCFYNLCK | |
| SCHEMBL25030582 | 0.78 | SRC (0.49) | ABL1PTK6SRCFYNLCK | |
| SCHEMBL26148542 | 0.77 | SRC (0.58) | ABL1PTK6SRCFYNLCK | |
| SCHEMBL18258356 | 0.77 | SRC (0.64) | FGFR2FGFR1FGFR3FGFR4ABL1 | |
| SCHEMBL18258360 | 0.76 | SRC (0.69) | ABL1PTK6SRCFYNLCK | |
| SCHEMBL21293809 | 0.76 | ADORA2A (0.48) | SRCFYNLCKRETCDC7 | |
| SCHEMBL18258367 | 0.76 | ABL1 (0.49) | ABL1PTK6SRCFYNLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107849050-B | Compound (I) | 爱丁堡大学董事会 | 2020-10-13 | — | — | CN | disclosed |