Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.40 |
| ▸ | ABAT | P80404 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL222221 | 0.83 | ALDH1A1 (0.74) | ALDH1A1TDP1MAPK1HTTNPSR1 | |
| SCHEMBL15458149 | 0.82 | ALDH5A1 (0.61) | ALDH1A1TDP1MAPK1HTTNPSR1 | |
| SCHEMBL1107500 | 0.81 | ALDH1A1 (0.70) | ALDH1A1TDP1MAPK1HTTNPSR1 | |
| Water SCHEMBL11592742 | 0.80 | ALDH1A1 (0.70) | ALDH1A1TDP1MAPK1HTTNPSR1 | |
| Water SCHEMBL11592745 | 0.80 | ALDH1A1 (0.70) | ALDH1A1TDP1MAPK1HTTNPSR1 | |
| SCHEMBL23388722 | 0.79 | TDP1 (0.52) | ALDH1A1TDP1MAPK1HTTLMNA | |
| Water SCHEMBL10349979 | 0.79 | ALDH1A1 (0.67) | ALDH1A1TDP1MAPK1HTTNPSR1 | |
| SCHEMBL56361 | 0.77 | MAPT (0.40) | ALDH1A1TDP1MAPK1HTTNPSR1 | |
| Xenygloxal SCHEMBL2110325 | 0.75 | ALDH1A1 (0.64) | ALDH1A1TDP1MAPK1HTTNPSR1 | |
| SCHEMBL934052 | 0.75 | MAPT (0.54) | ALDH1A1TDP1MAPK1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279802-B | Macromolecular compositions for binding small molecules | 德国科技术基金会 | 2024-04-12 | — | — | CN | claimed |
| CN-115279802-A | Macromolecular compositions for binding small molecules | 德国科技术基金会 | 2022-11-01 | — | — | CN | claimed |
| EP-4061859-A1 | MACROMOLECULAR COMPOSITIONS FOR BINDING SMALL MOLECULES | Stichting voor de Technische Wetenschappen (NL) | 2022-09-28 | — | — | EP | claimed |
| CN-115279802-B | Macromolecular compositions for binding small molecules | 德国科技术基金会 | 2024-04-12 | — | — | CN | disclosed |
| US-20230046628-A1 | Macromolecular compositions for binding small molecules | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2023-02-16 | — | — | US | disclosed |
| CN-115279802-A | Macromolecular compositions for binding small molecules | 德国科技术基金会 | 2022-11-01 | — | — | CN | disclosed |
| EP-4061859-A1 | MACROMOLECULAR COMPOSITIONS FOR BINDING SMALL MOLECULES | Stichting voor de Technische Wetenschappen (NL) | 2022-09-28 | — | — | EP | disclosed |