Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 12/20 | 0.55 |
| ▸ | CRBN | Q96SW2 | 9/20 | 0.55 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.55 |
| ▸ | AXL | P30530 | 2/20 | 0.49 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25031687 | 0.93 | STAT3 (0.53) | BRD4CRBNDDB1 | |
| SCHEMBL23766301 | 0.90 | CRBN (0.52) | BRD4CRBNDDB1MAP1LC3B | |
| SCHEMBL25030007 | 0.90 | STAT3 (0.54) | BRD4CRBNDDB1MAP1LC3B | |
| SCHEMBL23766284 | 0.90 | CRBN (0.53) | BRD4CRBNDDB1AXL | |
| SCHEMBL25031675 | 0.90 | CRBN (0.53) | BRD4CRBNDDB1AXL | |
| SCHEMBL26323878 | 0.89 | CRBN (0.63) | BRD4CRBNDDB1MAP1LC3B | |
| SCHEMBL26317744 | 0.89 | CRBN (0.63) | BRD4CRBNDDB1MAP1LC3B | |
| SCHEMBL26323874 | 0.89 | CRBN (0.63) | BRD4CRBNDDB1MAP1LC3B | |
| SCHEMBL26321035 | 0.89 | CRBN (0.63) | BRD4CRBNDDB1MAP1LC3B | |
| SCHEMBL17884407 | 0.89 | BRD4 (0.55) | BRD4CRBNDDB1AXLMAP1LC3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4134104-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | Eubulus Biotherapeutics Inc. (CN) | 2023-02-15 | — | — | EP | disclosed |