Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25030877 | 0.82 | — | — | |
| SCHEMBL30184473 | 0.82 | — | — | |
| SCHEMBL25032065 | 0.80 | IDO1 (0.34) | IDO1PDE3BPDE3ATAS1R3TAS1R1 | |
| SCHEMBL31304882 | 0.76 | NPC1 (0.30) | — | |
| SCHEMBL25032076 | 0.73 | ADRB1 (0.39) | PDE3BPDE3A | |
| SCHEMBL25032072 | 0.72 | IDO1 (0.33) | IDO1 | |
| SCHEMBL30184568 | 0.71 | LMNA (0.38) | — | |
| SCHEMBL25032392 | 0.71 | LMNA (0.38) | — | |
| SCHEMBL31304930 | 0.70 | RXFP1 (0.33) | — | |
| SCHEMBL25032069 | 0.68 | IDO1 (0.36) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016434-A1 | COMPOUNDS TARGETING MUTANT OF P53 | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2023-02-16 | — | — | WO | disclosed |