SCHEMBL25035174

SCHEMBL25035174

NC(=O)C(CCCCNC(=O)CCCCC1SCC2NC(=O)NC21)NC(=O)C(CCCCNCOCCCCCC1SCC2NC(=O)NC21)NC(=O)CCN1C(=O)C=CC1=O

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 7/20 0.50
▸ TDP1 Q9NUW8 1/20 0.50
▸ PLG P00747 1/20 0.47
▸ PRSS1 P07477 1/20 0.47
▸ PRSS2 P07478 1/20 0.47
▸ PRSS3 P35030 1/20 0.47
▸ TPSAB1 Q15661 1/20 0.47
▸ CNR1 P21554 2/20 0.47
▸ CASP3 P42574 2/20 0.45
▸ CASP1 P29466 1/20 0.45
▸ CASP2 P42575 1/20 0.45
▸ CASP7 P55210 1/20 0.45
▸ CASP8 Q14790 1/20 0.45
▸ PLCD1 P51178 1/20 0.45
▸ CAPN1 P07384 2/20 0.44
▸ PTPN1 P18031 2/20 0.43
▸ PTPN2 P17706 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24858269 0.93 TDP1 (0.57) FOLH1TDP1PLGPRSS1PRSS2
SCHEMBL24858268 0.93 TDP1 (0.57) FOLH1TDP1PLGPRSS1PRSS2
SCHEMBL22580893 0.86 PRSS1 (0.53) FOLH1TDP1PLGPRSS1PRSS2
SCHEMBL10172392 0.83 TDP1 (0.64) FOLH1TDP1CNR1CAPN1
SCHEMBL29357466 0.83 TDP1 (0.64) FOLH1TDP1CNR1CAPN1
SCHEMBL29434690 0.83 TDP1 (0.64) FOLH1TDP1CNR1CAPN1
SCHEMBL22580908 0.83 FOLH1 (0.51) FOLH1TDP1PLGPRSS1PRSS2
SCHEMBL24858698 0.82 TDP1 (0.48) FOLH1TDP1PLGPRSS1PRSS2
SCHEMBL16329737 0.82 FOLH1 (0.62) FOLH1TDP1PLGPRSS1PRSS2
SCHEMBL13125727 0.81 PKM (0.57) FOLH1TDP1PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230048956-A1 BIOTIN MOIETY-CONJUGATED POLYPEPTIDE AND PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION COMPRISING THE SAME D&D PHARMATECH INC. (KR) 2023-02-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230048956-A1 BIOTIN MOIETY-CONJUGATED POLYPEPTIDE AND PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION COMPRISING THE SAME VIP, BTD, HLCS FOLH1 558/4885TDP1 4789/4885PLG 1046/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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