SCHEMBL250353

SCHEMBL250353

Nc1ccc(-c2cccc(N)c2)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.76
TAAR1 Q96RJ0 2/20 0.64
CYP3A4 P08684 5/20 0.62
TDP1 Q9NUW8 2/20 0.62
HSD17B10 Q99714 1/20 0.62
CA12 O43570 1/20 0.61
CA1 P00915 1/20 0.61
CA2 P00918 1/20 0.61
CA9 Q16790 1/20 0.61
ALDH1A1 P00352 2/20 0.58
TP53 P04637 1/20 0.58
MAP4K4 O95819 3/20 0.57
CASP1 P29466 1/20 0.55
RECQL P46063 1/20 0.55
MEN1 O00255 2/20 0.55
CYP17A1 P05093 2/20 0.55
CYP19A1 P11511 2/20 0.55
CYP11B1 P15538 2/20 0.55
CYP11B2 P19099 2/20 0.55
KDM4E B2RXH2 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzidine SCHEMBL29236355 1.00 MAOA (0.76) MAOATAAR1CYP3A4TDP1HSD17B10
SCHEMBL31264296 1.00 MAOA (0.76) MAOATAAR1CYP3A4TDP1HSD17B10
SCHEMBL29115269 1.00 MAOA (0.76) MAOATAAR1CYP3A4TDP1HSD17B10
SCHEMBL29350106 1.00 MAOA (0.76) MAOATAAR1CYP3A4TDP1HSD17B10
SCHEMBL12253551 1.00 MAOA (0.76) MAOATAAR1CYP3A4TDP1HSD17B10
Water SCHEMBL7219757 0.97 MAOA (0.73) MAOATAAR1CYP3A4TDP1HSD17B10
SCHEMBL18960514 0.97 MAOA (0.73) MAOATAAR1CYP3A4TDP1HSD17B10
Ammonia Solution, Strong SCHEMBL21295984 0.97 MAOA (0.73) MAOATAAR1CYP3A4TDP1HSD17B10
Water SCHEMBL2447360 0.97 MAOA (0.73) MAOATAAR1CYP3A4TDP1HSD17B10
Water SCHEMBL29017536 0.97 MAOA (0.73) MAOATAAR1CYP3A4TDP1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 886 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260015454-A1 HIGH PERFORMANCE, AMBIENT CURE POLYURETHANES COMPRISING POLYCAPROLACTONE POLYOLS INGEVITY UK LTD (GB) 2026-01-15 US claimed
EP-4594381-A1 NOVEL POLYURETHANE OR POLYURETHANE-UREA COMPOSITION WITH ENHANCED LOW TEMPERATURE PERFORMANCE Ingevity UK Ltd (GB) 2025-08-06 EP claimed
US-20250243313-A1 POLYCAPROLACTONE POLYOLS, ELASTOMERS, AND METHODS OF MAKING AND USING THE SAME INGEVITY UK LTD (GB) 2025-07-31 US claimed
WO-2025149744-A1 POLYCAPROLACTONE POLYOLS, POLYURETHANE DISPERSIONS, AND METHODS OF MAKING AND USING THE SAME INGEVITY UK LTD (GB) 2025-07-17 WO claimed
US-20250230274-A1 POLYCAPROLACTONE POLYOLS, POLYURETHANE DISPERSIONS, AND METHODS OF MAKING AND USING THE SAME INGEVITY UK LTD (GB) 2025-07-17 US claimed
CN-115926160-B Adhesive for silicon-carbon negative electrode of lithium ion battery and preparation method thereof 桂林电器科学研究院有限公司 2024-05-28 CN claimed
WO-2024068129-A1 NOVEL POLYURETHANE OR POLYURETHANE-UREA COMPOSITION WITH ENHANCED LOW TEMPERATURE PERFORMANCE INGEVITY UK LTD. (GB) 2024-04-04 WO claimed
US-20240110002-A1 NOVEL POLYURETHANE OR POLYURETHANE-UREA COMPOSITION WITH ENHANCED LOW TEMPERATURE PERFORMANCE INGEVITY UK LTD (GB) 2024-04-04 US claimed
CN-117460381-A Double-tooth passivated perovskite precursor composition, perovskite light absorption layer prepared from double-tooth passivated perovskite precursor composition and perovskite solar cell 兰州理工大学 2024-01-26 CN claimed
CN-116496319-A Phosphine reagent, preparation method thereof and application of phosphine reagent in preparation of quinoxaline compounds 波米科技有限公司 2023-07-28 CN claimed
WO-2005023901-A1 COPOLYETHERIMIDES GENERAL ELECTRIC COMPANY (US) 2005-03-17 WO claimed
WO-2005021618-A2 PHASE TRANSFER CATALYZED METHOD FOR PREPARATION OF POLYETEHRIMIDES GENERAL ELECTRIC COMPANY (US) 2005-03-10 WO claimed
US-20050049390-A1 Phase transfer catalyzed method for preparation of polyetherimides GENERAL ELECTRIC COMPANY 2005-03-03 US claimed
US-6849706-B1 Copolyetherimides GENERAL ELECTRIC COMPANY (US) 2005-02-01 US claimed
WO-1998014501-A1 PROCESS FOR THE PREPARATION OF THERMOTROPIC AROMATIC POLYESTERS DIRECTLY FROM DIALKYL AROMATIC ESTERS HOECHST CELANESE CORPORATION (US) 1998-04-09 WO claimed
US-5731401-A ONE STEP; HIGH MOLECULAR WEIGHT HOECHST CELANESE CORP. (US) 1998-03-24 US claimed
US-5459233-A High temperature engineering aromatic polyimides MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1995-10-17 US claimed
US-5288843-A Polymerizing 4,4'-bis(3-aminophenoxy)biphenyl, pyromellitic dianhydride and a different aromaticdiamine; engineering plastics; molding mateials; aerospace; heat resistance; melt processibility MITSUI TOATSU CHEMICALS, INC. (JP) 1994-02-22 US claimed
EP-0540608-A1 A PROCESS FOR PREPARING SUBDENIER FIBERS, PULP-LIKE SHORT FIBERS, FIBRIDS, ROVINGS AND MATS FROM ISOTROPIC POLYMER SOLUTIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-05-12 EP claimed
US-4269967-A HIGH PERMEABILITY TO WATER BAYER AKTIENGESELLSCHAFT (DE) 1981-05-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015454-A1 HIGH PERFORMANCE, AMBIENT CURE POLYURETHANES COMPRISING POLYCAPROLACTONE POLYOLS PUF60, MORF4L1, C9 MAOA 1471/4885TAAR1 1664/4885CYP3A4 1622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.