Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.77 |
| ▸ | MAPT | P10636 | 5/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.71 |
| ▸ | TP53 | P04637 | 2/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.71 |
| ▸ | ATM | Q13315 | 1/20 | 0.71 |
| ▸ | MAOB | P27338 | 11/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.57 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sappanone A Trimethyl Ether SCHEMBL25035400 | 0.83 | MAPT (1.00) | APPMAPTALDH1A1MAPK1TP53 | |
| Sappanone A Trimethyl Ether SCHEMBL14479888 | 0.83 | MAPT (1.00) | APPMAPTALDH1A1MAPK1TP53 | |
| Sappanone A Trimethyl Ether SCHEMBL30274257 | 0.83 | MAPT (1.00) | APPMAPTALDH1A1MAPK1TP53 | |
| SCHEMBL5725497 | 0.82 | MAPT (0.77) | APPMAPTALDH1A1MAPK1TP53 | |
| SCHEMBL8465773 | 0.82 | APP (0.79) | APPMAPTALDH1A1MAPK1TP53 | |
| SCHEMBL8465775 | 0.82 | APP (0.79) | APPMAPTALDH1A1MAPK1TP53 | |
| SCHEMBL5724831 | 0.75 | MAOB (0.67) | APPMAPTALDH1A1MAPK1TP53 | |
| SCHEMBL5725448 | 0.75 | MAOB (0.67) | APPMAPTALDH1A1MAPK1TP53 | |
| SCHEMBL25035409 | 0.74 | CXCL12 (0.80) | APPMAPTALDH1A1MAPK1TP53 | |
| SCHEMBL30274371 | 0.74 | CXCL12 (0.80) | APPMAPTALDH1A1MAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129076-A1 | FUSED TETRACYCLIC COMPOUNDS, COMPOSITIONS AND DIAGNOSTIC APPLICATIONS THEREOF | BENAZIR FATHIMA (IN) | 2025-04-24 | — | — | US | disclosed |
| WO-2023017548-A1 | FUSED TETRACYCLIC COMPOUNDS, COMPOSITIONS AND DIAGNOSTIC APPLICATIONS THEREOF | BENAZIR J DR FATHIMA (IN) | 2023-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250129076-A1 | FUSED TETRACYCLIC COMPOUNDS, COMPOSITIONS AND DIAGNOSTIC APPLICATIONS THEREOF | POLRMT, POLM, DNTT | APP 1479/4885MAPT 144/4885ALDH1A1 1893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.