Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 4/20 | 0.57 |
| ▸ | CA12 | O43570 | 4/20 | 0.53 |
| ▸ | CA1 | P00915 | 4/20 | 0.53 |
| ▸ | CA2 | P00918 | 4/20 | 0.53 |
| ▸ | CA7 | P43166 | 4/20 | 0.53 |
| ▸ | CA9 | Q16790 | 4/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | GUSB | P08236 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29541022 | 0.85 | HTT (0.62) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1091528 | 0.85 | HTT (0.62) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6742873 | 0.81 | MEN1 (0.56) | HTT | |
| SCHEMBL8169977 | 0.81 | CHRNA7 (0.40) | CHRNA7CA12CA1CA2CA7 | |
| SCHEMBL10768717 | 0.81 | CHRNA7 (0.46) | CHRNA7CA1CA2HTTCES2 | |
| SCHEMBL9602694 | 0.81 | ALDH1A1 (0.63) | CHRNA7CA12CA1CA2CA7 | |
| SCHEMBL7769565 | 0.79 | CA12 (0.61) | CHRNA7CA12CA1CA2CA7 | |
| SCHEMBL21496861 | 0.79 | CHRNA7 (0.55) | CHRNA7CA12CA1CA2CA7 | |
| SCHEMBL23506747 | 0.79 | HTT (0.41) | CHRNA7CA12CA1CA2CA7 | |
| SCHEMBL21018531 | 0.78 | HTT (0.68) | CHRNA7CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017548-A1 | FUSED TETRACYCLIC COMPOUNDS, COMPOSITIONS AND DIAGNOSTIC APPLICATIONS THEREOF | BENAZIR J DR FATHIMA (IN) | 2023-02-16 | — | — | WO | disclosed |