Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29773102 | 0.90 | MEN1 (0.54) | MEN1KMT2ARAB9AKDM4ELMNA | |
| SCHEMBL11213739 | 0.85 | CSNK2A1 (0.60) | MEN1KMT2ARAB9AKDM4ELMNA | |
| SCHEMBL11074148 | 0.84 | HPGD (0.61) | MEN1KMT2ARAB9AKDM4ELMNA | |
| SCHEMBL10786547 | 0.84 | CSNK2A1 (0.58) | MEN1KMT2ARAB9AKDM4ELMNA | |
| SCHEMBL11581510 | 0.82 | KMT2A (0.72) | MEN1KMT2ARAB9AKDM4ELMNA | |
| SCHEMBL25035384 | 0.81 | CHRNA7 (0.57) | HTT | |
| SCHEMBL8712689 | 0.81 | CSNK2A1 (0.55) | MEN1KMT2ARAB9AKDM4ELMNA | |
| SCHEMBL1305878 | 0.79 | CSNK2A1 (0.62) | MEN1KMT2ARAB9AKDM4ELMNA | |
| SCHEMBL29368656 | 0.79 | CSNK2A1 (0.62) | MEN1KMT2ARAB9AKDM4ELMNA | |
| Ethylene SCHEMBL11475437 | 0.79 | HPGD (0.56) | MEN1KMT2ARAB9AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689788-B1 | USING THIAZOLE OR PYROLE DERIVATIVES | UNIVERSITY OF FLORIDA | 2004-02-10 | — | — | US | disclosed |
| US-20030211978-A1 | Method and composition for treatment of inflammatory bowel disease | BERGERON RAYMOND J (US) | 2003-11-13 | — | — | US | disclosed |
| EP-1113789-A1 | METHOD AND COMPOSITION FOR TREATMENT OF INFLAMMATORY BOWEL DISEASE | UNIVERSITY OF FLORIDA (US) | 2001-07-11 | — | — | EP | disclosed |
| US-6159983-A | Method and composition for treatment of inflammatory bowel disease | UNIVERSITY OF FLORIDA (US) | 2000-12-12 | — | — | US | disclosed |
| WO-2000016765-A9 | METHOD AND COMPOSITION FOR TREATMENT OF INFLAMMATORY BOWEL DISEASE | UNIV FLORIDA (US) | 2000-10-05 | — | — | WO | disclosed |
| WO-2000016765-A1 | METHOD AND COMPOSITION FOR TREATMENT OF INFLAMMATORY BOWEL DISEASE | UNIVERSITY OF FLORIDA (US) | 2000-03-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030211978-A1 | Method and composition for treatment of inflammatory bowel disease | SLC10A2, FABP2, SI | MEN1 3930/4885KMT2A 4784/4885RAB9A 3977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.