Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD81 | P60033 | 2/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5165178 | 0.92 | CD81 (0.34) | CD81ICAM1GRIK2ALDH1A1GABRA1 | |
| SCHEMBL222817 | 0.92 | CD81 (0.34) | CD81ICAM1GRIK2 | |
| SCHEMBL15968781 | 0.92 | CD81 (0.34) | CD81ICAM1GRIK2 | |
| SCHEMBL5003950 | 0.91 | CD81 (0.36) | CD81ICAM1GRIK2LMNAALOX5 | |
| SCHEMBL25234936 | 0.90 | LMNA (0.38) | CD81ICAM1GRIK2LMNAALOX5 | |
| SCHEMBL1770285 | 0.90 | LMNA (0.38) | CD81ICAM1GRIK2LMNAALOX5 | |
| SCHEMBL16267791 | 0.90 | LMNA (0.38) | CD81ICAM1GRIK2LMNAALOX5 | |
| SCHEMBL9090277 | 0.90 | LMNA (0.38) | CD81ICAM1GRIK2LMNAALOX5 | |
| SCHEMBL464872 | 0.90 | LMNA (0.38) | CD81ICAM1GRIK2LMNAALOX5 | |
| SCHEMBL15968695 | 0.87 | ICAM1 (0.32) | CD81ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030354-B2 | 2-(5,5-Dimethylcyclopent-1-enyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; metabolic disorders such as type II diabetes | AMGEN INC. (US) | 2011-10-04 | — | — | US | disclosed |