Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 9/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | USP2 | O75604 | 6/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25036135 | 0.81 | CYP2D6 (0.43) | CYP2D6CYP3A4HIF1AALDH1A1USP2 | |
| SCHEMBL25870353 | 0.81 | POLB (0.46) | CYP2D6CYP3A4HIF1AALDH1A1MEN1 | |
| SCHEMBL17212824 | 0.80 | ALDH1A1 (0.56) | CYP2D6CYP3A4HIF1AALDH1A1USP2 | |
| SCHEMBL27425362 | 0.78 | CYP2D6 (0.41) | CYP2D6CYP3A4HIF1AALDH1A1USP2 | |
| SCHEMBL25036661 | 0.78 | CYP2D6 (0.41) | CYP2D6CYP3A4HIF1AALDH1A1USP2 | |
| SCHEMBL23553275 | 0.77 | ALDH1A1 (0.43) | CYP2D6CYP3A4HIF1AALDH1A1USP2 | |
| SCHEMBL26075032 | 0.77 | CYP2C19 (0.55) | CYP2D6CYP3A4HIF1AALDH1A1USP2 | |
| SCHEMBL27430619 | 0.77 | L3MBTL1 (0.47) | CYP2D6CYP3A4HIF1AALDH1A1MEN1 | |
| SCHEMBL13722312 | 0.76 | ALDH1A1 (0.54) | CYP2D6CYP3A4HIF1AALDH1A1USP2 | |
| SCHEMBL25135384 | 0.76 | CYP3A4 (0.58) | CYP2D6CYP3A4HIF1AALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023019166-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | CALICO LIFE SCIENCES LLC (US) | 2023-02-16 | — | — | WO | disclosed |