Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 15/20 | 0.58 |
| ▸ | DDB1 | Q16531 | 14/20 | 0.58 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30273824 | 1.00 | CRBN (0.58) | CRBNDDB1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL23541139 | 0.91 | DDB1 (0.64) | CRBNDDB1NR1H2NR1H3RXRA | |
| SCHEMBL23842108 | 0.89 | DDB1 (0.72) | CRBNDDB1 | |
| SCHEMBL30273602 | 0.88 | DDB1 (0.53) | CRBNDDB1 | |
| SCHEMBL25036606 | 0.86 | CRBN (0.58) | CRBNDDB1 | |
| SCHEMBL31397004 | 0.86 | CRBN (0.58) | CRBNDDB1RXRARXRB | |
| SCHEMBL25036702 | 0.85 | CRBN (0.57) | CRBNDDB1 | |
| SCHEMBL23540585 | 0.84 | CRBN (0.62) | CRBNDDB1RXRARXRB | |
| SCHEMBL24818103 | 0.83 | CRBN (0.70) | CRBNDDB1 | |
| SCHEMBL23541177 | 0.83 | DDB1 (0.54) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023019166-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | CALICO LIFE SCIENCES LLC (US) | 2023-02-16 | — | — | WO | disclosed |