Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK2 | P49760 | 2/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.46 |
| ▸ | AKT2 | P31751 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 2/20 | 0.40 |
| ▸ | B3GNT2 | Q9NY97 | 2/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PAK4 | O96013 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22716907 | 0.82 | HAVCR2 (0.48) | CLK2DYRK1ACLK4HAVCR2LMNA | |
| SCHEMBL16997508 | 0.81 | DAO (0.62) | DAOHPGDAURKAB3GNT2 | |
| SCHEMBL31189202 | 0.80 | METAP2 (0.42) | HAVCR2LMNAHPGDAURKACDK9 | |
| SCHEMBL22716853 | 0.80 | METAP2 (0.42) | HAVCR2LMNAHPGDAURKACDK9 | |
| SCHEMBL4957725 | 0.80 | AKT2 (0.41) | CLK2DYRK1ACLK4AKT2OPRM1 | |
| SCHEMBL16997516 | 0.79 | DAO (0.60) | DAOLMNAAURKA | |
| SCHEMBL1519715 | 0.79 | LMNA (0.56) | CLK2DYRK1ACLK4AKT2OPRM1 | |
| SCHEMBL29414385 | 0.79 | LMNA (0.56) | CLK2DYRK1ACLK4AKT2OPRM1 | |
| SCHEMBL16997512 | 0.77 | PDE3B (0.45) | HAVCR2HPGDMAPT | |
| SCHEMBL24116887 | 0.75 | AKT2 (0.43) | CLK2DYRK1ACLK4AKT2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023019166-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | CALICO LIFE SCIENCES LLC (US) | 2023-02-16 | — | — | WO | disclosed |