Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GRM6 | O15303 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESRRG | P62508 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30273615 | 0.90 | PTPN1 (0.47) | PTPN1ALOX5APFEN1ACLYMAPT | |
| SCHEMBL25034776 | 0.90 | PTPN1 (0.47) | PTPN1ALOX5APFEN1ACLYMAPT | |
| SCHEMBL30274194 | 0.88 | PTPN1 (0.45) | PTPN1ALOX5APFEN1ACLYMAPT | |
| SCHEMBL25036186 | 0.88 | PTPN1 (0.45) | PTPN1ALOX5APFEN1ACLYMAPT | |
| SCHEMBL30273913 | 0.85 | PTPN1 (0.44) | PTPN1MAPTLMNAHPGDNPSR1 | |
| SCHEMBL30273918 | 0.85 | PTPN1 (0.44) | PTPN1MAPTLMNAHPGDNPSR1 | |
| SCHEMBL25036178 | 0.85 | PTPN1 (0.44) | PTPN1MAPTLMNAHPGDNPSR1 | |
| SCHEMBL25036303 | 0.80 | PTPN1 (0.45) | PTPN1MAPTHPGDGRM6ESR1 | |
| SCHEMBL25036333 | 0.80 | PTPN1 (0.48) | PTPN1ALOX5APFEN1MAPTLMNA | |
| SCHEMBL25036613 | 0.79 | PTPN1 (0.36) | PTPN1ACLYMAPTLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023019166-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | CALICO LIFE SCIENCES LLC (US) | 2023-02-16 | — | — | WO | disclosed |