Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.52 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 4/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.49 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.49 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | IL1B | P01584 | 1/20 | 0.48 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23540907 | 0.91 | CRBN (0.50) | CRBNALKBRD4STAT3DDB1 | |
| SCHEMBL25539454 | 0.89 | MAP1LC3B (0.59) | CRBNBRD4STAT3DDB1MAP1LC3B | |
| SCHEMBL21997107 | 0.89 | CRBN (0.52) | CRBNBRD4STAT3DDB1MAP1LC3B | |
| SCHEMBL23696490 | 0.88 | MAP1LC3B (0.54) | CRBNBRD4STAT3DDB1MAP1LC3B | |
| SCHEMBL19585396 | 0.88 | CRBN (0.54) | CRBNBRD4STAT3DDB1MAP1LC3B | |
| SCHEMBL20260448 | 0.87 | CRBN (0.58) | CRBNBRD4STAT3DDB1MAP1LC3B | |
| SCHEMBL30936855 | 0.87 | STAT3 (0.55) | CRBNBRD4STAT3DDB1MAP1LC3B | |
| SCHEMBL28909808 | 0.86 | MAP1LC3B (0.53) | CRBNSTAT3DDB1MAP1LC3BIKZF3 | |
| SCHEMBL27404250 | 0.86 | CRBN (0.66) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL30042075 | 0.86 | MAP1LC3B (0.53) | CRBNSTAT3DDB1MAP1LC3BIKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023019166-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | CALICO LIFE SCIENCES LLC (US) | 2023-02-16 | — | — | WO | disclosed |
| WO-2023019166-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | CALICO LIFE SCIENCES LLC (US) | 2023-02-16 | — | — | WO | disclosed |