Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP1LC3B | Q9GZQ8 | 8/20 | 0.53 |
| ▸ | CRBN | Q96SW2 | 8/20 | 0.52 |
| ▸ | GPX4 | P36969 | 1/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.49 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.48 |
| ▸ | GRAMD1A | Q96CP6 | 1/20 | 0.48 |
| ▸ | AXL | P30530 | 2/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30042075 | 1.00 | MAP1LC3B (0.53) | MAP1LC3BCRBNGPX4STAT3DDB1 | |
| SCHEMBL25539454 | 0.94 | MAP1LC3B (0.59) | MAP1LC3BCRBNSTAT3DDB1IKZF3 | |
| SCHEMBL25325954 | 0.92 | MAP1LC3B (0.62) | MAP1LC3BCRBNSTAT3DDB1IKZF3 | |
| SCHEMBL28434584 | 0.89 | MAP1LC3B (0.56) | MAP1LC3BCRBN | |
| SCHEMBL26814283 | 0.88 | CRBN (0.51) | MAP1LC3BCRBNGPX4STAT3DDB1 | |
| SCHEMBL25575056 | 0.87 | CRBN (0.49) | MAP1LC3BCRBNDDB1IKZF3JAK2 | |
| SCHEMBL23696490 | 0.87 | MAP1LC3B (0.54) | MAP1LC3BCRBNSTAT3DDB1IKZF3 | |
| SCHEMBL21997600 | 0.87 | STAT3 (0.53) | MAP1LC3BCRBNSTAT3DDB1GRAMD1A | |
| SCHEMBL34464358 | 0.87 | STAT3 (0.53) | MAP1LC3BCRBNSTAT3DDB1GRAMD1A | |
| SCHEMBL25327072 | 0.87 | MAP1LC3B (0.59) | MAP1LC3BCRBNSTAT3DDB1IKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461335-A | BCL-2 protein inhibitors | 里科瑞尔姆IP控股有限责任公司 | 2022-12-09 | — | — | CN | disclosed |