Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 6/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 6/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25039167 | 0.85 | PTPN7 (0.44) | PTPN7DUSP3ARCTSSCTSK | |
| SCHEMBL2600031 | 0.80 | PTPN7 (0.47) | PTPN7DUSP3ARNR3C2P2RX7 | |
| SCHEMBL2600223 | 0.80 | CTSS (0.46) | PTPN7DUSP3ARCTSSCTSK | |
| SCHEMBL19772156 | 0.77 | ESR1 (0.45) | — | |
| SCHEMBL1721015 | 0.77 | SLC6A2 (0.48) | PTPN7DUSP3ARNR3C2SLC6A4 | |
| SCHEMBL19251186 | 0.76 | PTPN7 (0.41) | PTPN7DUSP3ARCTSSCTSK | |
| SCHEMBL5023454 | 0.76 | AR (0.48) | PTPN7DUSP3ARNR3C2P2RX7 | |
| SCHEMBL10299806 | 0.76 | AR (0.48) | PTPN7DUSP3ARNR3C2P2RX7 | |
| SCHEMBL13821426 | 0.74 | RIPK1 (0.47) | RIPK1 | |
| SCHEMBL19309519 | 0.74 | HTR2A (0.49) | NR3C2SLC6A4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4134076-A1 | THERAPY FOR INHIBITION OF SINGLE-STRANDED RNA VIRUS REPLICATION | Redhill Biopharma Ltd. (IL) | 2023-02-15 | — | — | EP | disclosed |