Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22704140 | 0.91 | NPC1 (0.40) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL21185628 | 0.89 | MAPT (0.43) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL21753503 | 0.89 | MAPT (0.43) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL29154994 | 0.86 | GAA (0.45) | MAPTL3MBTL1GAAMEN1KMT2A | |
| SCHEMBL25037571 | 0.79 | MAPT (0.39) | MAPTMEN1KMT2AALDH1A1ABCB1 | |
| SCHEMBL16559311 | 0.79 | MAPT (0.39) | MAPTMEN1KMT2AALDH1A1ABCB1 | |
| SCHEMBL973145 | 0.77 | GAA (0.53) | MAPTL3MBTL1GAAMEN1KMT2A | |
| SCHEMBL8190181 | 0.77 | GAA (0.53) | MAPTL3MBTL1GAAMEN1KMT2A | |
| SCHEMBL973146 | 0.77 | GAA (0.53) | MAPTL3MBTL1GAAMEN1KMT2A | |
| SCHEMBL20877908 | 0.76 | PPARA (0.43) | MEN1KMT2AALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016296-A1 | HETEROCYCLIC COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2023-02-16 | — | — | WO | disclosed |