Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16559311 | 1.00 | MAPT (0.39) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL16561964 | 0.82 | CTSK (0.36) | MAPTKMT2AALDH1A1CTSK | |
| SCHEMBL16577823 | 0.82 | CTSK (0.36) | MAPTKMT2AALDH1A1CTSK | |
| SCHEMBL22704140 | 0.81 | NPC1 (0.40) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL14908440 | 0.80 | MAPT (0.64) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL21185628 | 0.79 | MAPT (0.43) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL21753503 | 0.79 | MAPT (0.43) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL25037566 | 0.79 | MAPT (0.43) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL30645094 | 0.78 | MAPT (0.41) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL30645091 | 0.78 | MAPT (0.41) | MAPTNPC1RAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016296-A1 | HETEROCYCLIC COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2023-02-16 | — | — | WO | disclosed |