Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 4/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17758698 | 0.76 | TYR (0.44) | MEN1KMT2AMAPTESR1ESR2 | |
| SCHEMBL10356413 | 0.75 | ESR1 (0.42) | MEN1KMT2AMAPTESR1ESR2 | |
| SCHEMBL11115405 | 0.73 | TYR (0.49) | MEN1KMT2AMAPTESR1ESR2 | |
| SCHEMBL2946516 | 0.72 | TYR (0.49) | MEN1KMT2AMAPTESR1ESR2 | |
| SCHEMBL3435872 | 0.72 | TYR (0.47) | MEN1KMT2AMAPTSHBGESR1 | |
| SCHEMBL3700326 | 0.71 | TYR (0.40) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL25037508 | 0.71 | ESR1 (0.49) | MEN1KMT2AMAPTSHBGESR1 | |
| SCHEMBL70826 | 0.71 | SHBG (0.53) | MEN1KMT2AMAPTSHBGESR1 | |
| SCHEMBL11708960 | 0.71 | TYR (0.45) | MEN1KMT2AMAPTSHBGESR1 | |
| SCHEMBL4064869 | 0.70 | ESR1 (0.56) | MEN1KMT2AMAPTSHBGESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4134076-A1 | THERAPY FOR INHIBITION OF SINGLE-STRANDED RNA VIRUS REPLICATION | Redhill Biopharma Ltd. (IL) | 2023-02-15 | — | — | EP | disclosed |