SCHEMBL3435872

SCHEMBL3435872

CCC(C)(C)c1ccc(O)cc1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 4/20 0.47
ALOX15 P16050 3/20 0.47
ALDH1A1 P00352 2/20 0.47
HTT P42858 2/20 0.47
LMNA P02545 2/20 0.47
HSD17B10 Q99714 2/20 0.47
NR1I2 O75469 1/20 0.47
CYP2C9 P11712 1/20 0.47
MIF P14174 1/20 0.47
NFE2L2 Q16236 1/20 0.47
HSP90AB1 P08238 1/20 0.41
ESR1 P03372 4/20 0.40
MAPT P10636 2/20 0.39
KDM4E B2RXH2 1/20 0.39
CYP1A2 P05177 1/20 0.39
ATP2A2 P16615 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ATP2A3 Q93084 1/20 0.39
ESR2 Q92731 3/20 0.39
MEN1 O00255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3958496 0.85 TYR (0.48) TYRALOX15ALDH1A1HTTLMNA
SCHEMBL17758698 0.84 TYR (0.44) TYRALOX15ALDH1A1HTTLMNA
SCHEMBL30026979 0.83 ALDH1A1 (0.63) TYRALOX15ALDH1A1HTTLMNA
SCHEMBL133971 0.83 ALDH1A1 (0.63) TYRALOX15ALDH1A1HTTLMNA
SCHEMBL11708960 0.82 TYR (0.45) TYRALOX15ALDH1A1HTTLMNA
SCHEMBL30893091 0.82 TRPA1 (0.46) ALOX15ALDH1A1LMNAHSD17B10ESR1
SCHEMBL4403912 0.82 ESR2 (0.42) TYRALOX15ALDH1A1HTTLMNA
SCHEMBL4399345 0.82 TRPA1 (0.46) ALOX15ALDH1A1LMNAHSD17B10ESR1
SCHEMBL70826 0.82 SHBG (0.53) TYRALOX15ALDH1A1HTTLMNA
SCHEMBL1900996 0.82 SMN1; SMN2 (0.44) ALOX15ALDH1A1HTTLMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11129781-B2 Agent for hair deforming treatment KAO CORPORATION (JP) 2021-09-28 US disclosed
US-11045402-B2 Hair cosmetic composition KAO CORPORATION (JP) 2021-06-29 US disclosed
US-10959925-B2 Hair cosmetic composition KAO CORPORATION (JP) 2021-03-30 US disclosed
EP-3228302-B1 HAIR DEFORMATION TREATMENT AGENT KAO CORP (JP) 2020-09-02 EP disclosed
CN-106999382-B Hair deforming agent 花王株式会社 2020-07-10 CN disclosed
CN-106999380-B Hair deforming agent 花王株式会社 2020-05-05 CN disclosed
US-20190290564-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2019-09-26 US disclosed
US-20190254943-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2019-08-22 US disclosed
US-20190224093-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2019-07-25 US disclosed
US-20190125052-A1 METHOD FOR TREATING HAIR KAO CORPORATION (JP) 2019-05-02 US disclosed
US-20180311129-A1 AGENT FOR HAIR DEFORMING TREATMENT KAO CORPORATION (JP) 2018-11-01 US disclosed
WO-2017207768-A1 METHOD FOR TREATING HAIR KAO CORPORATION (JP) 2017-12-07 WO disclosed
WO-2017207786-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2017-12-07 WO disclosed
WO-2017207767-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2017-12-07 WO disclosed
WO-2017207799-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2017-12-07 WO disclosed
EP-3228302-A1 HAIR DEFORMATION TREATMENT AGENT Kao Corporation (JP) 2017-10-11 EP disclosed
EP-3228300-A1 HAIR DEFORMATION TREATMENT AGENT Kao Corporation (JP) 2017-10-11 EP disclosed
US-20160137771-A1 COMPOUND CONTAINING PHENOLIC HYDROXYL GROUP, PHENOLIC RESIN, CURABLE COMPOSITION, CURED PRODUCT THEREOF, SEMICONDUCTOR SEALING MATERIAL, AND PRINTED CIRCUIT BOARD DIC CORPORATION (JP) 2016-05-19 US disclosed
US-20120094235-A1 ACTINIC-RAY- OR RADIATION-SENSITIVE RESIN COMPOSITION AND METHOD OF FORMING PATTERN USING THE COMPOSITION FUJIFILM CORPORATION (JP) 2012-04-19 US disclosed
US-4271059-A Color-developing composition for pressure-sensitive recording sheet material and process for the preparation thereof containing phenolic resin and hindered phenol MITSUI TOATSU CHEMICALS INC. (JP) 1981-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11045402-B2 Hair cosmetic composition CUTA, GRHPR, POLR1C TYR 6/4885ALOX15 2041/4885ALDH1A1 1188/4885
US-10959925-B2 Hair cosmetic composition CUTA, POLR1C, GRHPR TYR 4/4885ALOX15 2570/4885ALDH1A1 932/4885
US-20190254943-A1 HAIR COSMETIC COMPOSITION CUTA, POLR1C, GRHPR TYR 4/4885ALOX15 2570/4885ALDH1A1 932/4885
US-20180311129-A1 AGENT FOR HAIR DEFORMING TREATMENT COL1A1, COL2A1, GRHPR TYR 217/4885ALOX15 1186/4885ALDH1A1 99/4885
US-20190125052-A1 METHOD FOR TREATING HAIR GRHPR, TYR, POLR1C TYR 2/4885ALOX15 2603/4885ALDH1A1 740/4885
US-20190224093-A1 HAIR COSMETIC COMPOSITION CUTA, GRHPR, POLR1C TYR 6/4885ALOX15 2041/4885ALDH1A1 1188/4885
US-11129781-B2 Agent for hair deforming treatment GRHPR, SLC26A4, COL1A1 TYR 98/4885ALOX15 3131/4885ALDH1A1 1297/4885
US-20190290564-A1 HAIR COSMETIC COMPOSITION GRHPR, POLR1C, TYR TYR 3/4885ALOX15 2221/4885ALDH1A1 689/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.