Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.40 |
| ▸ | KHK | P50053 | 2/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30279264 | 1.00 | TRPV3 (0.40) | TRPV3KHKHRH4MAP4K4KDM4E | |
| SCHEMBL25039643 | 0.89 | TRPV3 (0.41) | TRPV3HRH4MAP4K4KDM4EMAPT | |
| SCHEMBL30279005 | 0.88 | TRPV3 (0.41) | TRPV3KHKHRH4MAP4K4KDM4E | |
| SCHEMBL25039287 | 0.88 | TRPV3 (0.41) | TRPV3KHKHRH4MAP4K4KDM4E | |
| SCHEMBL25039426 | 0.83 | CHRM3 (0.43) | TRPV3HRH4MAP4K4KDM4EMAPT | |
| SCHEMBL30279179 | 0.82 | KHK (0.38) | KHKHRH4HRH3HTR3EMEN1 | |
| SCHEMBL25039350 | 0.82 | KHK (0.38) | KHKHRH4HRH3HTR3EMEN1 | |
| SCHEMBL30279002 | 0.82 | KHK (0.34) | KHKHRH4HRH3CCNT1CDK4 | |
| SCHEMBL25039812 | 0.82 | KHK (0.34) | KHKHRH4HRH3CCNT1CDK4 | |
| SCHEMBL25040001 | 0.80 | KHK (0.33) | KHKHRH4KMT2APAK4PAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016447-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-02-16 | — | — | WO | disclosed |