Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 3/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | CD38 | P28907 | 1/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | AOC1 | P19801 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30279264 | 0.89 | TRPV3 (0.40) | TRPV3HRH4KDM4EMAPTHTR3A | |
| SCHEMBL25039467 | 0.89 | TRPV3 (0.40) | TRPV3HRH4KDM4EMAPTHTR3A | |
| SCHEMBL25041785 | 0.84 | HPGDS (0.39) | HRH4HTR3AMEN1KMT2AGAA | |
| SCHEMBL25039825 | 0.81 | HRH4 (0.32) | HRH4HTR3AMEN1KMT2APTGS2 | |
| SCHEMBL25041766 | 0.78 | HSD11B1 (0.42) | MAP4K4 | |
| SCHEMBL25042439 | 0.77 | KDM4E (0.38) | HRH4KDM4EMEN1KMT2AGAA | |
| SCHEMBL25042256 | 0.77 | MAPT (0.54) | TRPV3KDM4EMAPTMEN1KMT2A | |
| SCHEMBL25039287 | 0.76 | TRPV3 (0.41) | TRPV3HRH4KDM4EMAPTHTR3A | |
| SCHEMBL30279005 | 0.76 | TRPV3 (0.41) | TRPV3HRH4KDM4EMAPTHTR3A | |
| SCHEMBL31206186 | 0.76 | CRHR1 (0.37) | TRPV3KDM4EMAPTGAAPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016447-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-02-16 | — | — | WO | disclosed |