Azetirelin

Azetirelin

SCHEMBL250397

NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CC(=O)N1

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TRHR P34981 6/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Azetirelin SCHEMBL10703548 1.00 TRHR (0.62) TRHR
Azetirelin SCHEMBL4958204 1.00 TRHR (0.62) TRHR
Azetirelin SCHEMBL7265691 1.00 TRHR (0.62) TRHR
Azetirelin SCHEMBL27999417 1.00 TRHR (0.62) TRHR
Azetirelin SCHEMBL4960774 0.99 TRHR (0.61) TRHR
Protirelin SCHEMBL2182035 0.92 TRHR (0.71) TRHR
Protirelin SCHEMBL20659679 0.92 TRHR (0.71) TRHR
Protirelin SCHEMBL14280929 0.92 TRHR (0.71) TRHR
Protirelin SCHEMBL11798811 0.92 TRHR (0.71) TRHR
Protirelin SCHEMBL8364920 0.92 TRHR (0.71) TRHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 462 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220133627-A1 Stable Therapeutic Formulations ALZA CORP (US) 2022-05-05 — — US claimed
US-9421351-B2 Self-actuating applicator for microprojection array ALZA CORPORATION (US) 2016-08-23 — — US claimed
US-8920817-B2 Formulations for coated microprojections containing non-volatile counterions ALZA CORPORATION (US) 2014-12-30 — — US claimed
EP-1680154-B1 SELF-ACTUATING APPLICATOR FOR MICROPROJECTION ARRAY ALZA CORP (US) 2012-01-04 — — EP claimed
US-20100221305-A1 Formulations for coated microprojections containing non-volatile counterions ALZA CORPORATION (US) 2010-09-02 — — US claimed
US-20090117158-A1 Transdermal sustained release drug delivery ALZA CORPORATION 2009-05-07 — — US claimed
EP-1981547-A4 STABLE THERAPEUTIC FORMULATIONS ALZA CORP (US) 2009-05-06 — — EP claimed
WO-2009054988-A1 TRANSDERMAL SUSTAINED RELEASE DRUG DELIVERY ALZA CORPORATION (US) 2009-04-30 — — WO claimed
EP-1981547-A2 STABLE THERAPEUTIC FORMULATIONS ALZA CORPORATION (US) 2008-10-22 — — EP claimed
EP-1924364-A1 COATABLE TRANSDERMAL DELIVERY MICROPROJECTION ASSEMBLY Alza Corporation (US) 2008-05-28 — — EP claimed
US-20050049549-A1 Method and device for enhancing transdermal agent flux ALZA CORPORATION 2005-03-03 — — US claimed
WO-2005016440-A1 METHOD AND DEVICE FOR ENHANCING TRANSDERMAL AGENT FLUX ALZA CORPORATION (US) 2005-02-24 — — WO claimed
WO-2005016441-A1 METHOD AND DEVICE FOR ENHANCING TRANSDERMAL AGENT FLUX ALZA CORPORATION (US) 2005-02-24 — — WO claimed
US-20050031676-A1 Method and device for enhancing transdermal agent flux ALZA CORPORATION 2005-02-10 — — US claimed
WO-2005004729-A1 METHOD FOR COATING SKIN PIERCING MICROPROJECTIONS ALZA CORPORATION (US) 2005-01-20 — — WO claimed
WO-2005004842-A2 FORMULATIONS FOR COATED MICROPROJECTIONS CONTAINING NON-VOLATILE COUNTERIONS ALZA CORPORATION (US) 2005-01-20 — — WO claimed
US-20040265365-A1 Method for coating skin piercing microprojections ALZA CORPORATION 2004-12-30 — — US claimed
US-20040265354-A1 Transdermal drug delivery device having stratum corneum-piercing microprojections; pH stability and solubility when dried; ZOSANO PHARMA CORPORATION 2004-12-30 — — US claimed
EP-0225796-A2 Novel crystals of N alpha-[[(S)-4-oxo-2-azetidinyl]-carbonyl]-L-histidyl-L-prolinamide and process for producing the crystals YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1987-06-16 — — EP claimed
EP-0123444-A1 4-Substituted-2-azetidinone compound, process of producing the compounds, and medicaments containing the compounds YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1984-10-31 — — EP claimed
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