Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25038513 | 1.00 | APLNR (0.39) | APLNRSMN1; SMN2SMYD3HTR2BTMEM97 | |
| SCHEMBL13621107 | 1.00 | APLNR (0.39) | APLNRSMN1; SMN2SMYD3HTR2BTMEM97 | |
| SCHEMBL20609823 | 0.87 | NCF1 (0.38) | APLNRNCF1 | |
| SCHEMBL17052883 | 0.87 | NCF1 (0.38) | APLNRNCF1 | |
| Hydrochloric Acid SCHEMBL29043572 | 0.85 | NCF1 (0.37) | APLNRNCF1 | |
| SCHEMBL20610155 | 0.83 | APLNR (0.39) | APLNRNCF1CA1CA2 | |
| SCHEMBL25040749 | 0.81 | SMN1; SMN2 (0.35) | SMN1; SMN2SMYD3ATML3MBTL1 | |
| SCHEMBL25041101 | 0.81 | SMN1; SMN2 (0.35) | SMN1; SMN2SMYD3ATML3MBTL1 | |
| SCHEMBL8320328 | 0.81 | SMN1; SMN2 (0.35) | SMN1; SMN2SMYD3ATML3MBTL1 | |
| SCHEMBL24027196 | 0.79 | SMN1; SMN2 (0.34) | SMN1; SMN2SMYD3ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023018812-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2023-02-16 | — | — | WO | disclosed |