SCHEMBL25040583

SCHEMBL25040583

COC(=O)N1CC(C)=C(C(C)O)C1=O

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
KDM4E B2RXH2 1/20 0.33
PHGDH O43175 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25040572 0.73 MEN1 (0.31) MEN1KMT2AKDM4E
SCHEMBL25038288 0.72 KDM4E (0.33) MEN1KMT2AKDM4E
SCHEMBL29314726 0.66
SCHEMBL12254228 0.63 MEN1 (0.39) MEN1KMT2AKDM4E
SCHEMBL27364280 0.62 KMT2A (0.38) MEN1KMT2AKDM4E
SCHEMBL11576073 0.62 MEN1 (0.38) MEN1KMT2AKDM4E
SCHEMBL11357164 0.61 KMT2A (0.40) MEN1KMT2AKDM4E
SCHEMBL25091841 0.61 KDM4E (0.37) MEN1KMT2AKDM4E
SCHEMBL4104481 0.61 MEN1 (0.34) MEN1KMT2AKDM4E
SCHEMBL866289 0.60 LMNA (0.53) MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239745-A1 METHOD FOR SYNTHESIZING BILIRUBIN Bilix Co., Ltd. (KR) 2024-07-18 US disclosed
US-20240239745-A1 METHOD FOR SYNTHESIZING BILIRUBIN Bilix Co., Ltd. (KR) 2024-07-18 US disclosed
WO-2023018215-A1 METHOD FOR SYNTHESIZING BILIRUBIN 주식회사 빌릭스 2023-02-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239745-A1 METHOD FOR SYNTHESIZING BILIRUBIN CYP7A1, UGT1A3, UGT1A1 MEN1 3067/4885KMT2A 2003/4885KDM4E 3251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.