SCHEMBL4104481

SCHEMBL4104481

COC(=O)N1CC(=O)N=NC1=O

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
ADORA3 P0DMS8 1/20 0.32
TSHR P16473 1/20 0.31
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11357164 0.66 KMT2A (0.40) MEN1KMT2ATSHRKDM4E
SCHEMBL12254228 0.64 MEN1 (0.39) MEN1KMT2AADORA3TSHRKDM4E
SCHEMBL25038288 0.63 KDM4E (0.33) MEN1KMT2AKDM4E
SCHEMBL11576073 0.63 MEN1 (0.38) MEN1KMT2AADORA3TSHRKDM4E
SCHEMBL17014920 0.61
SCHEMBL25040572 0.61 MEN1 (0.31) MEN1KMT2AKDM4E
SCHEMBL25040583 0.61 MEN1 (0.34) MEN1KMT2AKDM4E
SCHEMBL866289 0.60 LMNA (0.53) MEN1KMT2ATSHRKDM4E
SCHEMBL9589828 0.60 NPSR1 (0.49) MEN1KMT2ATSHRKDM4E
SCHEMBL3362031 0.60 NAAA (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090221690-A1 Pharmaceutical Composition for the Prevention/Treatment of Bone Disorders and a Process for the Preparation Thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (US) 2009-09-03 US disclosed
EP-1993579-A2 A PHARMACEUTICAL COMPOSITION FOR THE PREVENTION/TREATMENT OF BONE DISORDERS AND A PROCESS FOR THE PREPARATION THEREOF Council of Scientific and Industrial Research (IN) 2008-11-26 EP disclosed
WO-2007099432-A2 PHARMACEUTICAL COMPOSITION CONTAINING BUTEA ISOFLAVONES FOR THE PREVENTION /TREATMENT OF BONE DISORDERS AND A PROCESS FOR THE PREPARATION THEREOF COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2007-09-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090221690-A1 Pharmaceutical Composition for the Prevention/Treatment of Bone Disorders and a Process for the Preparation Thereof SOST, BPGM, PTMS MEN1 197/4885KMT2A 4140/4885ADORA3 1505/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.