Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25895221 | 0.85 | MEN1 (0.40) | MEN1KMT2ASMN1; SMN2HSD17B10GAA | |
| SCHEMBL25972675 | 0.82 | BCHE (0.42) | MEN1KMT2ASMN1; SMN2HSD17B10GAA | |
| SCHEMBL25900443 | 0.81 | PDE4B (0.37) | MEN1KMT2ASMN1; SMN2HSD17B10GAA | |
| SCHEMBL20063362 | 0.79 | PKM (0.38) | MEN1KMT2ASMN1; SMN2HSD17B10GAA | |
| SCHEMBL20063342 | 0.79 | PKM (0.38) | MEN1KMT2ASMN1; SMN2HSD17B10GAA | |
| SCHEMBL22152623 | 0.78 | HRH3 (0.38) | MEN1KMT2ASMN1; SMN2HSD17B10GAA | |
| SCHEMBL25895223 | 0.78 | MEN1 (0.41) | MEN1KMT2ASMN1; SMN2HSD17B10GAA | |
| SCHEMBL23323563 | 0.77 | MEN1 (0.34) | MEN1KMT2ASMN1; SMN2HSD17B10GAA | |
| SCHEMBL23342020 | 0.76 | CHRNB2 (0.37) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL771222 | 0.75 | BCHE (0.36) | MEN1KMT2ASMN1; SMN2HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023015559-A1 | MACROCYCLE COMPOUNDS AS INHIBITORS OF RAS | NUTSHELL BIOTECH (SHANGHAI) CO., LTD. (CN) | 2023-02-16 | — | — | WO | disclosed |