Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ACACA | Q13085 | 3/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25042771 | 0.88 | MGLL (0.47) | MGLLHPGDMEN1KMT2ATSHR | |
| SCHEMBL25042657 | 0.81 | TEAD1 (0.51) | MGLLSCN9ATEAD1TEAD4TEAD2 | |
| SCHEMBL25042658 | 0.77 | NOTUM (0.41) | SCN9AALDH1A1LMNAHTTTEAD1 | |
| SCHEMBL25042677 | 0.76 | MGLL (0.52) | MGLLHPGDMRGPRX4PDK2MEN1 | |
| SCHEMBL25043183 | 0.75 | NPSR1 (0.49) | HPGDMRGPRX4PDK2SCN9ATEAD1 | |
| SCHEMBL25041616 | 0.73 | TEAD1 (0.53) | MGLLHPGDMRGPRX4PDK2MEN1 | |
| SCHEMBL30561334 | 0.70 | PDK2 (0.44) | MGLLHPGDMRGPRX4PDK2GAA | |
| SCHEMBL25380656 | 0.70 | PDK2 (0.44) | MGLLHPGDMRGPRX4PDK2GAA | |
| SCHEMBL25043186 | 0.69 | HPGD (0.48) | HPGDMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL30561434 | 0.69 | KDM1A (0.47) | HPGDMRGPRX4MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016562-A1 | POLYCYCLIC COMPOUND AND USE THEREOF | 浙江同源康医药股份有限公司 | 2023-02-16 | — | — | WO | disclosed |