Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 1/20 | 0.51 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.51 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.51 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25042658 | 0.85 | NOTUM (0.41) | TEAD1TEAD4TEAD2TEAD3SCN9A | |
| SCHEMBL25043183 | 0.82 | NPSR1 (0.49) | TEAD1TEAD4TEAD2TEAD3SCN9A | |
| SCHEMBL25041563 | 0.81 | MGLL (0.50) | TEAD1TEAD4TEAD2TEAD3MGLL | |
| SCHEMBL122436 | 0.80 | MGLL (0.57) | TEAD1TEAD4TEAD2TEAD3SRD5A2 | |
| SCHEMBL25042771 | 0.78 | MGLL (0.47) | MGLLSCN9A | |
| SCHEMBL30561336 | 0.77 | TEAD1 (0.67) | TEAD1TEAD4TEAD2TEAD3SRD5A2 | |
| SCHEMBL25381821 | 0.77 | TEAD1 (0.67) | TEAD1TEAD4TEAD2TEAD3SRD5A2 | |
| SCHEMBL6840348 | 0.75 | KMT2A (0.53) | TEAD1TEAD4TEAD2TEAD3SRD5A2 | |
| SCHEMBL122663 | 0.74 | HSD17B10 (0.72) | TEAD1TEAD4TEAD2TEAD3RXRA | |
| SCHEMBL29280306 | 0.74 | SRD5A2 (0.49) | TEAD1TEAD4TEAD2TEAD3SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016562-A1 | POLYCYCLIC COMPOUND AND USE THEREOF | 浙江同源康医药股份有限公司 | 2023-02-16 | — | — | WO | disclosed |