Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | TTK | P33981 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | GAK | O14976 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25039943 | 0.89 | PTK2 (0.38) | PTK2ACHEBACE1SMN1; SMN2MAPT | |
| SCHEMBL30279160 | 0.89 | PTK2 (0.38) | PTK2ACHEBACE1SMN1; SMN2MAPT | |
| SCHEMBL25042227 | 0.78 | ACHE (0.43) | ACHEBACE1PDE4DSMN1; SMN2HPGD | |
| SCHEMBL25042300 | 0.77 | KMT2A (0.37) | TTKALKKDM4EUSP2ALDH1A1 | |
| SCHEMBL13462989 | 0.75 | MAPT (0.38) | TTKMAPTLRRK2 | |
| SCHEMBL30279087 | 0.75 | MAPT (0.38) | TTKMAPTLRRK2 | |
| SCHEMBL25039475 | 0.75 | MAPT (0.38) | TTKMAPTLRRK2 | |
| SCHEMBL13438919 | 0.75 | MAPT (0.38) | TTKMAPTLRRK2 | |
| SCHEMBL13462695 | 0.75 | MAPT (0.38) | TTKMAPTLRRK2 | |
| SCHEMBL11935237 | 0.75 | MAPT (0.38) | TTKMAPTLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016447-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-02-16 | — | — | WO | disclosed |