Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GAK | O14976 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GALR1 | P47211 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30279289 | 0.89 | BACE1 (0.42) | ACHEBACE1NPSR1L3MBTL1ATM | |
| SCHEMBL25039941 | 0.89 | BACE1 (0.42) | ACHEBACE1NPSR1L3MBTL1ATM | |
| SCHEMBL25039949 | 0.89 | BACE1 (0.42) | ACHEBACE1NPSR1L3MBTL1ATM | |
| SCHEMBL25042117 | 0.87 | ACHE (0.43) | ACHEBACE1NPSR1L3MBTL1ATM | |
| SCHEMBL25039766 | 0.84 | ALDH1A1 (0.41) | ACHEBACE1L3MBTL1KMT2AMEN1 | |
| SCHEMBL25041758 | 0.78 | PTK2 (0.39) | ACHEBACE1NPSR1L3MBTL1GAK | |
| SCHEMBL25042422 | 0.74 | KDM4C (0.36) | KMT2AMEN1NPC1TSHRKDM4E | |
| SCHEMBL25039295 | 0.74 | KDM4E (0.35) | BACE1NPSR1KMT2ATDP1TSHR | |
| SCHEMBL11935236 | 0.74 | KDM4E (0.35) | BACE1NPSR1KMT2ATDP1TSHR | |
| SCHEMBL13438914 | 0.74 | KDM4E (0.35) | BACE1NPSR1KMT2ATDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016447-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-02-16 | — | — | WO | disclosed |