Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 8/20 | 0.43 |
| ▸ | BTK | Q06187 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31205821 | 1.00 | KDM1A (0.44) | KDM1AMAOBDRD2BTKDRD3 | |
| SCHEMBL31206020 | 0.88 | RAB9A (0.48) | KDM1AMAOBDRD2BTKDRD3 | |
| SCHEMBL27983784 | 0.86 | KDM1A (0.45) | KDM1AMAOBDRD2BTKDRD3 | |
| SCHEMBL25041798 | 0.85 | KDM1A (0.43) | KDM1AMAOBDRD2BTKDRD3 | |
| SCHEMBL25042395 | 0.84 | KDM1A (0.45) | KDM1AMAOBDRD2BTKDRD3 | |
| SCHEMBL31206112 | 0.83 | KDM1A (0.47) | KDM1AMAOBDRD2BTKDRD3 | |
| SCHEMBL25042392 | 0.81 | KDM1A (0.45) | KDM1AMAOBDRD2BTKDRD3 | |
| SCHEMBL31206117 | 0.81 | KDM1A (0.42) | KDM1AMAOBDRD2BTKDRD3 | |
| SCHEMBL25041582 | 0.81 | KDM1A (0.42) | KDM1AMAOBDRD2BTKDRD3 | |
| SCHEMBL31206154 | 0.80 | NPC1 (0.48) | KDM1AMAOBDRD2BTKDRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016447-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-02-16 | — | — | WO | disclosed |