Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31206020 | 0.89 | RAB9A (0.48) | KDM1AMAOBALDH1A1MAPTHTT | |
| SCHEMBL31206112 | 0.84 | KDM1A (0.47) | KDM1AMAOBALDH1A1BTKKMT2A | |
| SCHEMBL31205821 | 0.84 | KDM1A (0.44) | KDM1AMAOBALDH1A1MAPTHTT | |
| SCHEMBL25042393 | 0.84 | KDM1A (0.44) | KDM1AMAOBALDH1A1MAPTHTT | |
| SCHEMBL23720467 | 0.83 | KDM1A (0.49) | KDM1AMAOBALDH1A1MAPTHTT | |
| SCHEMBL30556445 | 0.83 | KDM1A (0.49) | KDM1AMAOBALDH1A1MAPTHTT | |
| SCHEMBL25042392 | 0.82 | KDM1A (0.45) | KDM1AMAOBALDH1A1MAPTHTT | |
| SCHEMBL31206091 | 0.82 | KDM1A (0.44) | KDM1AMAOBALDH1A1MAPTHTT | |
| SCHEMBL31206154 | 0.81 | NPC1 (0.48) | KDM1AMAOBALDH1A1MAPTHTT | |
| SCHEMBL848356 | 0.81 | ALDH1A1 (0.64) | ALDH1A1MAPTHTTRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016447-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-02-16 | — | — | WO | disclosed |