Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | PDE2A | O00408 | 4/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25043532 | 0.89 | SLC6A3 (0.38) | THRBSLC6A3SLC6A4PDE2ASLC6A2 | |
| SCHEMBL25043528 | 0.89 | PPARD (0.35) | THRBSLC6A3SLC6A4PDE2AEPHX2 | |
| SCHEMBL25043354 | 0.88 | SLC6A3 (0.38) | THRBSLC6A3SLC6A4PDE2ASLC6A2 | |
| SCHEMBL25042481 | 0.87 | SLC6A3 (0.40) | THRBSLC6A3SLC6A4PDE2ASLC6A2 | |
| SCHEMBL25043357 | 0.86 | PDE2A (0.37) | THRBPDE2AAPPPTPN1L3MBTL1 | |
| SCHEMBL25043239 | 0.86 | SLC6A3 (0.39) | SLC6A3SLC6A4PDE2ASLC6A2OPRM1 | |
| SCHEMBL26942730 | 0.85 | PPARD (0.36) | THRBSLC6A3SLC6A4PDE2AEPHX2 | |
| SCHEMBL25043328 | 0.84 | CDK1 (0.36) | THRBSLC6A3SLC6A4PDE2AEPHX2 | |
| SCHEMBL25043446 | 0.83 | SLC6A3 (0.34) | THRBSLC6A3SLC6A4PDE2AAPP | |
| SCHEMBL24803200 | 0.83 | SLC6A3 (0.38) | THRBSLC6A3SLC6A4PDE2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017269-A1 | DERIVATIVES OF ITACONIC ACID AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | SITRYX THERAPEUTICS LIMITED (GB) | 2023-02-16 | — | — | WO | disclosed |