Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.59 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TDO2 | P48775 | 7/20 | 0.53 |
| ▸ | PRKCB | P05771 | 1/20 | 0.51 |
| ▸ | CDK4 | P11802 | 1/20 | 0.51 |
| ▸ | CCND1 | P24385 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30620453 | 0.86 | IMPDH2 (0.56) | ASH1LIMPDH2NR4A2MAPK1HSD17B10 | |
| SCHEMBL15949729 | 0.85 | ASH1L (0.55) | ASH1LIMPDH2NR4A2MAPK1HSD17B10 | |
| SCHEMBL18418496 | 0.80 | NR4A2 (0.68) | IMPDH2NR4A2MAPK1HSD17B10TDO2 | |
| SCHEMBL31517811 | 0.80 | NR4A2 (0.68) | IMPDH2NR4A2MAPK1HSD17B10TDO2 | |
| SCHEMBL26703619 | 0.80 | DYRK1A (0.66) | IMPDH2MAPK1HSD17B10TDO2 | |
| SCHEMBL6586643 | 0.79 | ASH1L (0.59) | ASH1LIMPDH2NR4A2MAPK1HSD17B10 | |
| SCHEMBL23259083 | 0.79 | ASH1L (0.59) | ASH1LCDK4CCND1ATM | |
| SCHEMBL29824426 | 0.79 | ASH1L (0.63) | ASH1LIMPDH2NR4A2MAPK1HSD17B10 | |
| SCHEMBL23649189 | 0.79 | ASH1L (0.63) | ASH1LIMPDH2NR4A2MAPK1HSD17B10 | |
| SCHEMBL30695578 | 0.79 | ASH1L (0.59) | ASH1LIMPDH2NR4A2MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4134364-A2 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2023-02-15 | — | — | EP | disclosed |