Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | USP19 | O94966 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15000803 | 0.91 | KDM4E (0.33) | CYP11B2USP19 | |
| SCHEMBL25045245 | 0.87 | USP19 (0.31) | USP19 | |
| SCHEMBL1583511 | 0.82 | USP19 (0.35) | USP19 | |
| Hydrochloric Acid SCHEMBL2650625 | 0.80 | USP19 (0.34) | USP19 | |
| SCHEMBL4173987 | 0.79 | USP19 (0.41) | HSD11B1PIM1USP19 | |
| SCHEMBL1583393 | 0.79 | USP19 (0.38) | PIM1USP19 | |
| SCHEMBL28466818 | 0.78 | USP19 (0.42) | HSD11B1PIM1USP19 | |
| Hydrochloric Acid SCHEMBL1584061 | 0.78 | USP19 (0.38) | PIM1USP19 | |
| Bromide SCHEMBL28432857 | 0.78 | USP19 (0.40) | HSD11B1PIM1USP19 | |
| Bromide SCHEMBL28429216 | 0.76 | USP19 (0.42) | HSD11B1PIM1USP19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703765-B | Substituted triazole derivative, preparation method, pharmaceutical composition and application thereof | 上海赛默罗生物科技有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-115703765-A | Substituted triazole derivative, preparation method, pharmaceutical composition and application thereof | 上海赛默罗生物科技有限公司 | 2023-02-17 | — | — | CN | disclosed |
| WO-2023016521-A1 | SUBSTITUTED TRIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 上海赛默罗生物科技有限公司 | 2023-02-16 | — | — | WO | disclosed |