Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP19 | O94966 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1584061 | 0.98 | USP19 (0.38) | USP19DRD2P2RX7PIM1OPRM1 | |
| SCHEMBL4173987 | 0.96 | USP19 (0.41) | USP19DRD2P2RX7PIM1OPRM1 | |
| Bromide SCHEMBL28432857 | 0.95 | USP19 (0.40) | USP19DRD2P2RX7PIM1OPRM1 | |
| SCHEMBL28466818 | 0.95 | USP19 (0.42) | USP19P2RX7PIM1OPRM1OPRD1 | |
| Bromide SCHEMBL28429216 | 0.93 | USP19 (0.42) | USP19P2RX7PIM1OPRM1OPRD1 | |
| SCHEMBL1583511 | 0.93 | USP19 (0.35) | USP19DRD2P2RX7GRM2KDM4E | |
| Hydrochloric Acid SCHEMBL2650625 | 0.91 | USP19 (0.34) | USP19DRD2GRM2KDM4EL3MBTL1 | |
| SCHEMBL15000803 | 0.85 | KDM4E (0.33) | USP19DRD2GRM5KDM4E | |
| SCHEMBL25045245 | 0.81 | USP19 (0.31) | USP19 | |
| SCHEMBL25043883 | 0.79 | HSD11B1 (0.37) | USP19PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011041713-A2 | PIPERAZINYL ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-07 | — | — | WO | disclosed |