Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 11/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 10/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 8/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30282901 | 0.87 | GABRA5 (0.54) | GABRA5GABRB3GABRG2KCNH2 | |
| SCHEMBL25045396 | 0.87 | GABRA5 (0.44) | GABRA5GABRB3GABRG2KCNH2 | |
| SCHEMBL25044752 | 0.87 | GABRA5 (0.44) | GABRA5GABRB3GABRG2KCNH2L3MBTL1 | |
| SCHEMBL30283019 | 0.85 | GABRA5 (0.43) | GABRA5GABRB3GABRG2KCNH2 | |
| SCHEMBL25045401 | 0.85 | GABRA5 (0.43) | GABRA5GABRB3GABRG2KCNH2 | |
| SCHEMBL30236918 | 0.84 | GABRA5 (0.41) | GABRA5GABRB3GABRG2KCNH2RAB9A | |
| SCHEMBL21623964 | 0.84 | GABRA5 (0.43) | GABRA5GABRB3GABRG2KCNH2RXRA | |
| SCHEMBL30282856 | 0.84 | GABRA5 (0.43) | GABRA5GABRB3GABRG2KCNH2RXRA | |
| SCHEMBL25045127 | 0.83 | GABRA5 (0.41) | GABRA5GABRB3GABRG2KCNH2 | |
| SCHEMBL25045399 | 0.83 | GABRA5 (0.43) | GABRA5GABRB3GABRG2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016521-A1 | SUBSTITUTED TRIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 上海赛默罗生物科技有限公司 | 2023-02-16 | — | — | WO | disclosed |