Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 13/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 10/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 10/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25045401 | 0.88 | GABRA5 (0.43) | GABRA5GABRG2GABRB3KCNH2NOTUM | |
| SCHEMBL30283019 | 0.88 | GABRA5 (0.43) | GABRA5GABRG2GABRB3KCNH2NOTUM | |
| SCHEMBL25045399 | 0.88 | GABRA5 (0.43) | GABRA5GABRG2GABRB3KCNH2NOTUM | |
| SCHEMBL25045396 | 0.88 | GABRA5 (0.44) | GABRA5GABRG2GABRB3KCNH2NOTUM | |
| SCHEMBL25044752 | 0.88 | GABRA5 (0.44) | GABRA5GABRG2GABRB3KCNH2 | |
| SCHEMBL30282901 | 0.86 | GABRA5 (0.54) | GABRA5GABRG2GABRB3KCNH2 | |
| SCHEMBL2688352 | 0.86 | GABRA5 (0.54) | GABRA5GABRG2GABRB3KCNH2 | |
| SCHEMBL30236918 | 0.85 | GABRA5 (0.41) | GABRA5GABRG2GABRB3KCNH2 | |
| SCHEMBL25043835 | 0.85 | GABRA5 (0.38) | GABRA5GABRG2GABRB3KCNH2 | |
| SCHEMBL25044792 | 0.83 | GABRA5 (0.43) | GABRA5GABRG2GABRB3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016521-A1 | SUBSTITUTED TRIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 上海赛默罗生物科技有限公司 | 2023-02-16 | — | — | WO | disclosed |