⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23749729 | 0.64 | — | — | |
| SCHEMBL24599387 | 0.58 | — | — | |
| SCHEMBL23749856 | 0.54 | GLP1R (0.36) | — | |
| SCHEMBL29177228 | 0.47 | SOS1 (0.41) | — | |
| SCHEMBL17320328 | 0.46 | HTT (0.50) | — | |
| SCHEMBL26739507 | 0.46 | SOS1 (0.41) | — | |
| SCHEMBL13772553 | 0.45 | NISCH (0.38) | — | |
| SCHEMBL6407111 | 0.44 | SETD7 (0.54) | — | |
| SCHEMBL22993443 | 0.43 | MAOA (0.46) | — | |
| SCHEMBL22993430 | 0.43 | MAOA (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016546-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2023-02-16 | — | — | WO | disclosed |