Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT7 | O95251 | 20/20 | 0.70 |
| ▸ | KAT6A | Q92794 | 20/20 | 0.70 |
| ▸ | KAT6B | Q8WYB5 | 12/20 | 0.62 |
| ▸ | KAT5 | Q92993 | 10/20 | 0.62 |
| ▸ | KAT8 | Q9H7Z6 | 10/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801369 | 1.00 | KAT7 (0.70) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL30184738 | 0.95 | KAT6A (0.68) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL31028387 | 0.95 | KAT6A (0.68) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL25045832 | 0.95 | KAT6A (0.68) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL25928143 | 0.93 | KAT7 (0.65) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL25045851 | 0.92 | KAT6A (0.69) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL25045843 | 0.92 | KAT6A (0.69) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL30184731 | 0.91 | KAT7 (0.69) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL25439714 | 0.91 | KAT7 (0.69) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL25045968 | 0.91 | KAT7 (0.73) | KAT7KAT6AKAT6BKAT5KAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4385989-A1 | SULFONAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2024-06-19 | — | — | EP | disclosed |
| CN-117597341-A | Sulfonamide derivative, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-02-23 | — | — | CN | disclosed |
| WO-2023114710-A1 | FUSED BENZOISOXAZOLYL COMPOUNDS AS KAT6A INHIBITORS | AURIGENE ONCOLOGY LIMITED (IN) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023016484-A1 | SULFONAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 江苏恒瑞医药股份有限公司 | 2023-02-16 | — | — | WO | disclosed |