SCHEMBL30801369

SCHEMBL30801369

COc1ccccc1S(=O)(=O)Nc1noc2cc(Cn3cccn3)c3c(c12)OCC3

nearest known ligand 0.70

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KAT7 O95251 20/20 0.70
KAT6A Q92794 20/20 0.70
KAT6B Q8WYB5 12/20 0.62
KAT5 Q92993 10/20 0.62
KAT8 Q9H7Z6 10/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25045846 1.00 KAT7 (0.70) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL30184738 0.95 KAT6A (0.68) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31028387 0.95 KAT6A (0.68) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL25045832 0.95 KAT6A (0.68) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL25928143 0.93 KAT7 (0.65) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL25045851 0.92 KAT6A (0.69) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL25045843 0.92 KAT6A (0.69) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL30184731 0.91 KAT7 (0.69) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL25439714 0.91 KAT7 (0.69) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL25045968 0.91 KAT7 (0.73) KAT7KAT6AKAT6BKAT5KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250145637-A1 SULFONAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF JIANGSU HENGRUI PHARMACEUTICALS CO., LTD. (CN) 2025-05-08 US disclosed
CN-117597341-A Sulfonamide derivative, preparation method and application thereof in medicine 江苏恒瑞医药股份有限公司 2024-02-23 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250145637-A1 SULFONAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF SULT2A1, KAT8, TST KAT7 5/4885KAT6A 26/4885KAT6B 48/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.