Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 2/20 | 0.54 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.52 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.49 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047818 | 0.85 | ADK (0.50) | ADKADORA3ADORA2AADORA1NFKB1 | |
| SCHEMBL25046802 | 0.82 | PRMT5 (0.54) | METTL3PRMT5WDR77 | |
| SCHEMBL25047776 | 0.80 | PRMT5 (0.54) | METTL3PRMT5WDR77 | |
| SCHEMBL31618052 | 0.79 | PRMT5 (0.55) | METTL3PRMT5WDR77 | |
| SCHEMBL25048328 | 0.79 | PRMT5 (0.55) | METTL3PRMT5WDR77 | |
| SCHEMBL25048728 | 0.79 | PRMT5 (0.39) | ADKMETTL3ADORA2AADORA1NFKB1 | |
| SCHEMBL23982517 | 0.78 | ADK (0.73) | ADKMETTL3METTL14SLC29A1 | |
| SCHEMBL20419313 | 0.78 | ADK (0.73) | ADKMETTL3METTL14SLC29A1 | |
| SCHEMBL17816362 | 0.78 | ADK (0.73) | ADKMETTL3METTL14SLC29A1 | |
| SCHEMBL20419319 | 0.78 | ADK (0.73) | ADKMETTL3METTL14SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |