Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 5/20 | 0.47 |
| ▸ | EGFR | P00533 | 5/20 | 0.47 |
| ▸ | ABL2 | P42684 | 5/20 | 0.47 |
| ▸ | METTL3 | Q86U44 | 4/20 | 0.44 |
| ▸ | SRC | P12931 | 9/20 | 0.44 |
| ▸ | LCK | P06239 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | TEK | Q02763 | 2/20 | 0.43 |
| ▸ | HCK | P08631 | 1/20 | 0.43 |
| ▸ | ADK | P55263 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30941007 | 1.00 | CA2 (0.49) | CA2ABL1EGFRABL2METTL3 | |
| SCHEMBL25048825 | 0.95 | CA2 (0.52) | CA2ABL1EGFRABL2METTL3 | |
| SCHEMBL30941348 | 0.95 | CA2 (0.52) | CA2ABL1EGFRABL2METTL3 | |
| SCHEMBL30940792 | 0.91 | CA2 (0.45) | CA2ABL1EGFRABL2METTL3 | |
| SCHEMBL25046810 | 0.91 | CA2 (0.45) | CA2ABL1EGFRABL2METTL3 | |
| SCHEMBL25048714 | 0.91 | ABL1 (0.49) | CA2ABL1EGFRABL2METTL3 | |
| SCHEMBL31618011 | 0.91 | ABL1 (0.49) | CA2ABL1EGFRABL2METTL3 | |
| SCHEMBL25047789 | 0.89 | METTL3 (0.58) | CA2ABL1EGFRABL2METTL3 | |
| SCHEMBL30940795 | 0.89 | METTL3 (0.58) | CA2ABL1EGFRABL2METTL3 | |
| SCHEMBL25049329 | 0.88 | METTL3 (0.45) | CA2ABL1EGFRABL2METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |