Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 5/20 | 0.54 |
| ▸ | PI4KA | P42356 | 1/20 | 0.54 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.54 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.54 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | STAT6 | P42226 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047424 | 0.90 | ADK (0.45) | ADKPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL18572215 | 0.85 | PI4KA (0.56) | ADKPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL17816344 | 0.82 | ADK (0.78) | ADKALDH1A1TDP1HIF1ASTAT6 | |
| SCHEMBL18009847 | 0.79 | PI4KA (0.56) | ADKPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL90990 | 0.76 | ADK (0.67) | ADKPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL18009754 | 0.76 | PI4KA (0.55) | ADKPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL18571721 | 0.76 | PI4KA (0.66) | ADKPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL18535300 | 0.76 | PI4KA (0.55) | ADKPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL16120836 | 0.76 | PI4KA (0.55) | ADKPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL67029 | 0.76 | ADK (0.67) | ADKPI4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |