Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 7/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 6/20 | 0.35 |
| ▸ | JAK3 | P52333 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 2/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 2/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047945 | 0.96 | PRMT5 (0.36) | PRMT5WDR77JAK3NAMPTGPR119 | |
| SCHEMBL25047894 | 0.96 | PRMT5 (0.36) | PRMT5WDR77JAK3NAMPTGPR119 | |
| SCHEMBL25048437 | 0.91 | PRMT5 (0.34) | PRMT5WDR77JAK3NAMPTGPR119 | |
| SCHEMBL25048841 | 0.86 | PRMT5 (0.36) | PRMT5WDR77GPR119 | |
| SCHEMBL25048807 | 0.86 | NNMT (0.36) | PRMT5WDR77GPR119 | |
| SCHEMBL19344271 | 0.85 | PRMT5 (0.47) | PRMT5WDR77GPR119 | |
| SCHEMBL19344065 | 0.85 | PRMT5 (0.39) | PRMT5WDR77NAMPTGPR119CNR2 | |
| SCHEMBL25047504 | 0.82 | JAK3 (0.40) | PRMT5WDR77JAK3NAMPTGPR119 | |
| SCHEMBL19344268 | 0.79 | PRMT5 (0.45) | PRMT5WDR77GPR119 | |
| SCHEMBL19344069 | 0.79 | PRMT5 (0.36) | PRMT5GPR119CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |