Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 5/20 | 0.44 |
| ▸ | EGFR | P00533 | 5/20 | 0.44 |
| ▸ | ABL2 | P42684 | 5/20 | 0.44 |
| ▸ | SRC | P12931 | 9/20 | 0.42 |
| ▸ | LCK | P06239 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | TEK | Q02763 | 2/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | PRKCG | P05129 | 1/20 | 0.40 |
| ▸ | PRKCB | P05771 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCH | P24723 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 2/20 | 0.40 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048490 | 0.94 | ABL1 (0.43) | ABL1EGFRABL2SRCLCK | |
| SCHEMBL25048002 | 0.91 | RET (0.42) | ABL1EGFRABL2SRCLCK | |
| SCHEMBL25048005 | 0.86 | ABL1 (0.43) | ABL1EGFRABL2SRCLCK | |
| SCHEMBL25047965 | 0.85 | ABL1 (0.54) | ABL1EGFRABL2SRCLCK | |
| SCHEMBL30940999 | 0.84 | METTL3 (0.52) | METTL3PRMT5 | |
| SCHEMBL25046807 | 0.84 | METTL3 (0.52) | METTL3PRMT5 | |
| SCHEMBL25047988 | 0.83 | EGFR (0.46) | ABL1EGFRABL2SRCLCK | |
| SCHEMBL25048162 | 0.81 | METTL3 (0.46) | ABL1EGFRABL2SRCLCK | |
| SCHEMBL25048000 | 0.80 | METTL3 (0.44) | ABL1EGFRABL2SRCLCK | |
| SCHEMBL25046669 | 0.79 | METTL3 (0.40) | ABL1EGFRABL2IGF1RADCY5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |