Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 7/20 | 0.42 |
| ▸ | KIF5B | P33176 | 6/20 | 0.42 |
| ▸ | IGF1R | P08069 | 3/20 | 0.42 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | ABL1 | P00519 | 3/20 | 0.41 |
| ▸ | ABL2 | P42684 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 5/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 6/20 | 0.38 |
| ▸ | HCK | P08631 | 2/20 | 0.38 |
| ▸ | FLT3 | P36888 | 2/20 | 0.38 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CCDC6 | Q16204 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | LYN | P07948 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | BLK | P51451 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048490 | 0.91 | ABL1 (0.43) | RETIGF1REGFRABL1ABL2 | |
| SCHEMBL25047518 | 0.91 | ABL1 (0.44) | RETIGF1REGFRABL1ABL2 | |
| SCHEMBL25048000 | 0.90 | METTL3 (0.44) | RETKIF5BIGF1REGFRABL1 | |
| SCHEMBL30940806 | 0.86 | METTL3 (0.47) | RETKIF5B | |
| SCHEMBL25048880 | 0.86 | METTL3 (0.47) | RETKIF5B | |
| SCHEMBL25048005 | 0.80 | ABL1 (0.43) | RETIGF1REGFRABL1ABL2 | |
| SCHEMBL25047965 | 0.79 | ABL1 (0.54) | RETKIF5BIGF1REGFRABL1 | |
| SCHEMBL25048887 | 0.77 | METTL3 (0.49) | — | |
| SCHEMBL30941129 | 0.77 | METTL3 (0.49) | — | |
| SCHEMBL25047988 | 0.77 | EGFR (0.46) | IGF1REGFRABL1ABL2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |