Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 14/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 14/20 | 0.42 |
| ▸ | METTL3 | Q86U44 | 11/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25046676 | 0.91 | SRC (0.34) | PRMT5WDR77METTL3 | |
| SCHEMBL25048523 | 0.87 | ADK (0.39) | — | |
| SCHEMBL25047521 | 0.87 | PRMT5 (0.36) | PRMT5METTL3 | |
| SCHEMBL25048500 | 0.86 | SRC (0.33) | — | |
| SCHEMBL25048851 | 0.85 | SRC (0.32) | — | |
| SCHEMBL25046661 | 0.84 | SRC (0.32) | — | |
| SCHEMBL25047533 | 0.83 | PRMT5 (0.44) | PRMT5WDR77METTL3 | |
| SCHEMBL25048894 | 0.83 | METTL3 (0.39) | PRMT5WDR77METTL3 | |
| SCHEMBL25047933 | 0.82 | METTL3 (0.37) | METTL3 | |
| SCHEMBL31618034 | 0.82 | METTL3 (0.39) | PRMT5WDR77METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |